This book reports on cutting-edge research and best practices in the broad field of biomedical engineering. Based on the  XLVII Mexican Conference on Biomedical Engineering, CNIB 2024, held on November 7-9, 2024 in Hermosillo, Sonora, México, this first volume of the proceedings covers research topics in biomedical signal processing, computational biology and prosthetics, with applications of artificial intelligence for medical diagnosis, behavioral studies and more. All in all, this book provides a timely snapshot on state-of-the-art achievements in biomedical engineering and current challenges in the field. It addresses both researchers and professionals, and it is expected to foster future collaborations between the two groups, as well as international collaborations.