This is a collection of survey articles based on lectures presented at a colloquium and workshop in Geneva in 2003 to commemorate the 200th anniversary of the birth of Charles François Sturm. It aims at giving an overview of the development of Sturm-Liouville theory from its historical roots to present day research. It is the first time that such a comprehensive survey has been made available in compact form. The contributions come from internationally renowned experts and cover a wide range of developments of the theory. The book can therefore serve both as an introduction to Sturm-Liouville theory and as background for ongoing research. The volume is addressed to researchers in related areas, to advanced students and to those interested in the historical development of mathematics. The book will also be of interest to those involved in applications of the theory to diverse areas such as engineering, fluid dynamics and computational spectral analysis.