Stereoselective Syntheses of Tetrah - E-book

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Stereoselective Syntheses Of Tetrahydropyrans - ENG

Applications To The Synthesis Of (+)-leucascandrolide A, (+)-dactylolide And (Â±)-diospongin A

Kiyoun Lee

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Sinopsis

ISBN:	9783319044620
Formato:	ePub
Idioma:	Inglés
Editorial:	Springer Nature
Tema:	Ciencia
Subtema:	Química orgánica
Año de publicación:	2014-07-08

In his thesis, Kiyoun Lee describes his studies into tandem and organocatalytic oxa-conjugate addition reactions for the synthesis of complex tetrahydropyrans (THP). Readers gain insight into the new methods Lee employs for the synthesis of biologically interesting natural products including (+)-leucascandrolide A, (+)-dactylolide, and (Â±)diospongin A. The reactions Lee investigates are applicable to a broad range of substrates and proceed with excellent stereoselectivity. Moreover, the methodologies allow the synthesis of a wide range of THP-containing compounds. The development of reactions, such as those discussed by Lee, has the potential to impact natural product synthesis, pharmaceutical development and chemical biology.

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