This book contains the contributions presented at the 12th international KES conference on Smart Education and e-Learning (SEEL 2025). This book is being held on June 25?27, 2025, in Solin, Croatia, in both in-person and online modes. This book contains high-quality peer-reviewed papers that are grouped into several interconnected parts: Part 1?Smart Education, Part 2?Smart e-Learning, Part 3?Smart University, Part 4?Smart Education: Case Studies and Research, and Part 5?Smart Company: Case Studies and Research. This book serves as a useful source of research data and valuable information on current research projects, best practices, and case studies for faculty, scholars, Ph.D. students, administrators, and practitioners?all those who are interested in smart education, smart e-learning, smart university, and smart business/company paradigms, concepts, systems, and technology.