This book includes the proceedings of the Responsible Engineering and Living 2022 Symposium and Industry Summit. Molière holds each of us accountable when he asserted that, “It is not only for what we do that we are held responsible, but also for what we do not do.� Responsible Engineering and Living 2022 (REAL2022) strived to inspire every individual to practise and foster responsible engineering and living. Its proceedings brings all stakeholders, enthusiasts and experts from academia, industry, policy arenas, and general public, together to discuss challenges, sharpen existing solutions, and formulate novel means to advance responsible engineering and living. This symposium disseminates recent progress and promote collaborations to maximize opportunities for innovative solutions. Topics of interest include resource and energy conservation, waste reduction, nature-friendly engineering and architecture, and sustainable vibrant living.