Resistance to Molecular Therapies f - E-book

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Resistance To Molecular Therapies For Hepatocellular Carcinoma - ENG

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Sinopsis

ISBN:	9783319561974
Formato:	Page Fidelity
Idioma:	Inglés
Editorial:	Springer Nature
Tema:	Medicina
Subtema:	Oncología
Año de publicación:	2017-07-14

This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies.Â

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