Protein Quality Control in Neurodeg - E-book

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Protein Quality Control In Neurodegenerative Diseases - ENG

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Sinopsis

ISBN:	9783642279287
Formato:	ePub
Idioma:	Inglés
Editorial:	Springer Nature
Tema:	Medicina
Subtema:	Estudio Científico
Año de publicación:	2012-12-13

The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimers disease, Parkinsons disease, amyotrophic lateral sclerosis, Huntingtons disease, and other diseases of protein conformation.

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