Photopolymerizable Porous Polyorgan - E-book

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Photopolymerizable Porous Polyorganophosphazenes - ENG

Degradable Matrices For Tissue Engineering

Tamara Bernadette Aigner

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Sinopsis

ISBN:	9783658093204
Formato:	Page Fidelity
Idioma:	Inglés
Editorial:	Springer Nature
Tema:	Tecnología e ingeniería
Subtema:	Ciencia de los Materiales general
Año de publicación:	2015-03-11

Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes). In order to tailor their biological and chemical properties, she further modified these macromolecules by adding functional moieties via thiol-ene chemistry. The author used the same photochemistry for crosslinking to obtain a mechanically stable network. She further altered the degradation rate of the matrix as well as the mechanical properties by adding blending agents and created a porous matrix, which is necessary for cell invasion and communication, by a newly developed photocrosslinking particulate-leaching method. Thus, a modular hybrid system was established which is able to adapt to different microenvironments based upon tissue type.

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