Optimized Response-Adaptive Clinica - E-book

eBook

Optimized Response-adaptive Clinical Trials - ENG

Sequential Treatment Allocation Based On Markov Decision Problems

Thomas Ondra

eBook

$1,100.00

Disponible

Información adicional
Sinopsis

ISBN:	9783658083441
Formato:	Page Fidelity
Idioma:	Inglés
Editorial:	Springer Nature
Tema:	Matemáticas
Subtema:	Probabilidad y estadística general
Año de publicación:	2014-12-03

Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences.

eBooks