Multiple Testing Procedures with Ap - E-book

eBook

Multiple Testing Procedures With Applications To Genomics - ENG

Sandrine Dudoit; Mark J. van der Laan

eBook

$3,180.00

Disponible

Información adicional
Sinopsis

ISBN:	9780387493176
Formato:	Page Fidelity
Idioma:	Inglés
Editorial:	Springer Nature
Tema:	Ciencia
Subtema:	Ciencias de la Vida anatomía y fisiología
Año de publicación:	2007-12-18

This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.

eBooks