This book is the first authoritative book volume dedicated to the application of Mesotherapy in dermatology. This book provides an up-to-date and comprehensive overview of the basic structural component of Mesotherapy and its constitution from the chemical side of view, then we will discuss its role in cosmetic dermatology, facial rejuvenation, its anti-aging properties, and its role with hyaluronic acid and mesoneedling therapy for facial youthfulness. This volume will describe interplay of mesotherapy and other dermatological diseases such as alopecia hair loss, melasma, acne, psoriasis, and eczema. Chapters will address key issues, such as mesotherapy complications and urticaria that are caused because of it. In addition, the book will discuss severe acute caffeine poisoning due to intradermal mesotherapy injections and the use of mesotherapy as a lucrative business in the cosmetic industry. This book will be a valuable resource to dermatologists, general practitioners, dermatology residents, and medical students.