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| ISBN: | 9781118978313 |
|---|---|
| Formato: | ePub |
| Idioma: | Inglés |
| Editorial: | Wiley Global Research (STMS) |
| Tema: | Medicina |
| Subtema: | Farmacología |
| Año de publicación: | 2016-06-22 |
Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development. •   Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates •   Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair •   Introduces new pathways in therapeutic development and new mechanisms in drug development