Transplantation in South Asia faces unique immunological challenges, yet comprehensive data on genetic and epigenetic factors in the region remains sparse. This ground-breaking book addresses the critical need for a uniform approach to the immunological workup of transplant recipients and donors, tailored specifically for one of the world?s highest-volume transplantation regions. Drawing on insights from renowned immunologists, transplant physicians, and surgeons, the book provides an in-depth exploration of immune signatures in South Asian populations. It offers actionable guidance to optimize donor-recipient matching and minimize immune system activation during and after transplantation. Through a practical, case-based approach, the book delves into real-world immunological challenges and solutions, covering key topics such as immunosuppressive strategies for children, adults, older patients, and women with prior sensitization. Each chapter is designed to equip healthcare professionals with the tools to address complex scenarios with confidence. With over 650 transplantation centers in India alone, this essential resource is invaluable for trainees, nurses, technicians, and all members of the transplant team seeking to enhance their understanding of immunology in transplantation.