This book features an original selection of scientific chapters presented during ?HealthTech25?Global Summit of Digital Health?, held in Marrakech from April 16 to 18, 2025. The first day took place as part of GITEX Africa, under the High Patronage of His Majesty King Mohammed VI, followed by two days of sessions hosted at the Faculty of Medicine and Pharmacy, affiliated with Cadi Ayyad University of Marrakech, Morocco. The chapters in this book focus on ethical, regulatory, and organizational dimensions of digital health. Authors explore topics such as the governance of digital health systems, health data sovereignty, regulatory frameworks, equitable access to technology, and the resilience of health systems in the face of contemporary challenges. This book is intended for researchers, public health experts, policy makers, and stakeholders engaged in the critical analysis and structuring of digital health ecosystems.