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| ISBN: | 9783034806886 |
|---|---|
| Formato: | ePub |
| Idioma: | Inglés |
| Editorial: | Springer Nature |
| Tema: | Medicina |
| Subtema: | Inmunología |
| Año de publicación: | 2013-08-28 |
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.