This book discusses the outcomes of more than ten years of research in the southern tracts of the Amazon region, and addresses the expansion of the agricultural frontier, consolidation of the agribusiness-based economy, and expansion of regional infrastructure (roads, dams, urban centres, etc). It combines extensive empirical evidence with the international literature on frontier-making and regional Amazonian development, and adopts a critical politico-geographical perspective that will benefit scholars in various other disciplines. This book is intended to push the current theoretical and methodological boundaries regarding the controversies and impacts of agribusiness in the region. A new international scientific network, led by the author, is investigating the broader context of the themes analysed here.