Drug Metabolism and Pharmacokinetic - E-book

eBook

Drug Metabolism And Pharmacokinetics Quick Guide - ENG

Siamak Cyrus Khojasteh; Harvey Wong; Cornelis E. C. A. Hop

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Sinopsis

ISBN:	9781441956293
Formato:	ePub
Idioma:	Inglés
Editorial:	Springer Nature
Tema:	Medicina
Subtema:	Farmacología
Año de publicación:	2011-04-07

Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such asÂ pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. ItÂ covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall itÂ includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.

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