This book presents case studies to analyse the relationship between sustainability – environmental, social, institutional and economic – and digital innovation.  The respective contributions offer a contextualisation of the main present and future trends concerning these two elements, and present analyses from economic, technical, managerial, and social perspectives alike. The individual sections of the book focus on interactions between sustainability and digital innovation in existing organisations and highlight the new opportunities, challenges and threats that may emerge as a result. The contributions are mainly based on case studies and research conducted in Europe and Africa, with a few focusing on Southeast Asia and Central America, and were prepared by experts in the fields of Information Systems, Computer Science, Social Development, and Economics.