This book presents a comprehensive overview of the latest advancements in the field of cyber-physical systems, focusing on the transition from Industry 4.0 to Industry 5.0. This transition emphasizes the increased role of humans in the manufacturing process, the introduction of new technologies, and improvements in management and security. The book covers various topics, including neural network and synergetic approaches to solving problems, decentralized identifiers methods classification, identification of technological opportunities for enterprises, and cybernetic technologies to counter passive and active cyberattacks. This book is an essential resource for researchers, engineers, and students interested in the field of cyber-physical systems, as well as for professionals working in industries that are undergoing the transition from Industry 4.0 to Industry 5.0.