The Compound-Nuclear Reaction and Related Topics (CNR*) international workshop series was initiated in 2007 with a meeting near Yosemite National Park. It has since been held in Bordeaux (2009), Prague (2011), Sao Paulo (2013), Tokyo (2015), and Berkeley, California (2018). The workshop series brings together experts in nuclear theory, experiment, data evaluations, and applications, and fosters interactions among these groups. Topics of interest include: nuclear reaction mechanisms, optical model, direct reactions and the compound nucleus, pre-equilibrium reactions, fusion and fission, cross section measurements (direct and indirect methods), Hauser-Feshbach theory (limits and extensions), compound-nuclear decays, particle and gamma emission, level densities, strength functions, nuclear structure for compound-nuclear reactions, nuclear energy, nuclear astrophysics, and other topics. This peer-reviewed proceedings volume presents papers and poster summaries from the 6th International Workshop on Compound-Nuclear Reactions and Related Topics CNR*18, held on September 24-28, 2018, at Lawrence Berkeley National Lab, Berkeley, CA.